If you’re serious about gut health, muscle recovery, or immune support, chances are thorne l-glutamine (in capsules or in powder) has popped up on your radar. Whether you’re an athlete looking to bounce back quicker after workouts or someone simply wanting to support a healthier digestive system, this supplement has built a strong reputation—and for good reason. But what exactly is it? Let’s break it all down.
Table of Contents
What Is Thorne L-Glutamine?
Thorne L-Glutamine is a dietary supplement designed to support muscle recovery, gastrointestinal health, and immune function by providing a pure and bioavailable form of L-glutamine, the most abundant amino acid in the bloodstream. L-glutamine plays a crucial role in fueling intestinal cells, aiding nutrient absorption, supporting the gut lining, and enhancing immune cell function. It is especially beneficial during periods of physical stress, injury, or intense exercise when the body’s natural glutamine levels may be depleted.
Thorne offers L-Glutamine in two forms:
Thorne L-Glutamine Powder:

This form delivers a potent, pure dose of L-glutamine (about 5 grams per scoop) without any fillers or additives. It is designed to mix easily with water, juice, or smoothies, making it suitable for those who prefer a flexible dosing option. The powder supports muscle repair post-exercise and promotes overall gastrointestinal and immune health.
Thorne L-glutamine Capsules

Each capsule typically contains 500 mg of L-glutamine along with a hypromellose capsule shell and silicon dioxide as an anti-caking agent. The capsules are convenient for on-the-go use and are free from gluten, soy, and dairy. They are recommended to be taken multiple times daily or as directed by a healthcare professional.
Both forms are NSF Certified for Sport®, ensuring they meet high standards for purity and are free from banned substances, making them trusted choices for athletes and health-conscious individuals. Thorne’s commitment to quality includes rigorous testing and sourcing, providing a supplement that supports gut integrity, immune resilience, and muscle repair effectively and safely.
How Does Thorne L-Glutamine Work?
Thorne L-Glutamine works primarily by supporting two critical physiological functions: maintaining gut health and enhancing immune function, as well as aiding muscle recovery and tissue repair.
Supporting Gut and Immune Health
L-glutamine serves as a vital energy source for cells lining the gastrointestinal tract, particularly enterocytes (intestinal cells) and colonocytes. These cells rely heavily on glutamine to fuel their metabolism and maintain the integrity of the gut lining. When the gut barrier is compromised-due to stress, illness, or injury-intestinal permeability increases, allowing harmful bacteria and toxins to pass into the bloodstream. Supplemental L-glutamine helps restore the gut lining by providing fuel for rapid cell turnover and repair, reducing permeability and preventing bacterial translocation.
Additionally, L-glutamine supports immune cells in the gut-associated lymphoid tissue (GALT), which plays a key role in immune defense. It promotes the proliferation of lymphocytes and enhances the production of important immune signaling molecules like interleukin-2 and interferon-gamma. It also helps maintain secretory IgA, an antibody that prevents bacteria from adhering to mucosal surfaces. By boosting these immune responses, L-glutamine helps protect against infections and supports overall immune resilience.
Moreover, L-glutamine contributes to antioxidant defenses by increasing glutathione synthesis in intestinal cells, which reduces oxidative stress and helps maintain mucosal integrity. This antioxidant effect is particularly important in conditions like sickle cell disease, where oxidative damage is a major concern.
Aiding Muscle Recovery and Tissue Repair
L-glutamine is the most abundant amino acid in the bloodstream and plays a crucial role in protein synthesis and nitrogen transport. During periods of intense physical stress, such as strenuous exercise or injury, the body’s demand for glutamine increases as it supports muscle repair and recovery. Supplemental L-glutamine helps replenish depleted stores, sparing skeletal muscle from excessive breakdown.
By providing the necessary substrate for protein synthesis, L-glutamine facilitates tissue repair and muscle regeneration. This is particularly beneficial for athletes or individuals undergoing recovery from trauma or surgery, helping to reduce muscle soreness and improve healing.
Thorne L-Glutamine Ingredients
Thorne L-Glutamine is available in two main forms: capsules and powder, each with a straightforward ingredient profile focused on delivering pure L-glutamine to support gut health, immune function, and muscle recovery.
Ingredients in Thorne L-Glutamine Capsules:
- L-Glutamine (500 mg per capsule)
- Hypromellose (a plant-derived cellulose used for the capsule shell)
- Silicon Dioxide (an anti-caking agent to maintain powder flow and stability)
These capsules are free from common allergens such as gluten, soy, and dairy, making them suitable for vegetarians and those with sensitivities. Each container typically provides 90 servings, with a recommended dosage of one capsule three times daily or as advised by a healthcare professional.
Ingredients in Thorne L-Glutamine Powder:
- Pure L-Glutamine (approximately 5 grams per scoop)
The powder contains no additional fillers, binders, or additives, ensuring a clean supplement that mixes easily with water or other beverages. The slight difference between the scoop weight (around 5.7 grams) and the glutamine content (5 grams) accounts for formulation stability, ensuring the full dose is delivered throughout the product’s shelf life. This powder is also free from gluten, dairy, soy, and other common allergens.
Key Features:
- L-Glutamine is the most abundant amino acid in the body and serves as a primary fuel source for intestinal cells, supporting a healthy gut barrier and digestive function.
- It plays a crucial role in immune cell function and helps maintain overall cellular health.
- Supplementation is particularly beneficial for individuals experiencing physical stress, intense exercise, injury recovery, or gastrointestinal challenges.
- Both forms are designed to be hypoallergenic and suitable for those with dietary restrictions.
Thorne’s L-Glutamine products are manufactured under strict quality controls, adhering to Good Manufacturing Practices to ensure purity and potency. They provide a bioavailable form of L-glutamine that supports gut integrity, immune resilience, and muscle repair without unnecessary additives or allergens.
Thorne L-Glutamine Benefits
Let’s get into the good stuff—what you actually get from using this supplement.
Improved Gut Health
If you deal with digestive issues like bloating, discomfort, or leaky gut, this powder could help strengthen your intestinal lining. Glutamine fuels the cells that form your gut barrier, which helps keep harmful substances from sneaking into your bloodstream.
Faster Muscle Recovery
Athletes and fitness enthusiasts often turn to thorne l-glutamine powder post-workout. It supports quicker recovery, reduces soreness, and can help maintain muscle mass, especially during intense training cycles.
Immune Support
Your immune cells also rely on glutamine for energy. During times of stress or illness, supplementing can give your immune system a much-needed boost, keeping you from getting sidelined.
Supports Mental Clarity
While not its primary use, some users report feeling more mentally alert when taking glutamine. The reason? It can indirectly support brain function by promoting better gut health—part of the brain-gut connection.
Helpful During Illness or Recovery
If you’re healing from surgery, injury, or a chronic illness, glutamine supplementation may support overall recovery and help your body rebuild faster.
Possible Side Effects of Thorne L-Glutamine Powder
For most people, thorne l-glutamine powder is well-tolerated and safe. But like any supplement, it’s not completely risk-free.
Some users may experience:
- Mild stomach discomfort
- Headache
- Fatigue or dizziness in rare cases
If you have liver disease, kidney issues, or a history of seizures, check with your healthcare provider before starting. Also, pregnant or breastfeeding women should consult a doctor first.
As with any supplement, dosage matters. Stick to the recommended amount and avoid going overboard unless advised by a professional.
How To Use Thorne L-Glutamine Powder
Using this supplement is simple. Here’s what most people do:
- Dose: 1 scoop (5 grams) daily, or as directed by a healthcare provider.
- Timing: You can take it on an empty stomach, post-workout, or before bed—whenever it fits into your routine.
- Mixing: Stir it into water, juice, or a shake. Since it’s flavorless, it won’t alter the taste of your drink.
Some people like to split the dose—half in the morning and half in the evening—especially if they’re taking it for gut health or muscle recovery.
How To Use Thorne L-Glutamine Capsules
To use Thorne L-Glutamine capsules, the general recommendation is to take one capsule three times daily, or follow the specific guidance provided by your healthcare practitioner or performance professional. Each capsule contains 500 mg of pure L-glutamine. This dosage supports replenishing glutamine levels in the body, which is important for gut health, immune function, and muscle recovery, especially during times of physical stress or injury.
If swallowing capsules is difficult, the capsule can be opened and its contents sprinkled onto food or mixed into a drink, which should be consumed immediately. It is advised not to exceed the recommended dose and to keep the supplement out of reach of children. Pregnant or nursing individuals, or those taking medications, should consult their healthcare provider before use.
In summary:
- Take 1 capsule three times daily, or as directed by a healthcare professional.
- Capsules contain 500 mg L-glutamine each.
- Capsules can be opened and mixed with food or drinks if needed.
- Do not exceed the recommended dose.
- Consult a healthcare provider if pregnant, nursing, or on medication.
This regimen helps maintain healthy glutamine levels to support intestinal cell health, immune system function, and muscle repair following physical stress or exercise.
Thorne L-Glutamine Reviews
Thorne L-Glutamine has received generally positive reviews from users, particularly for its role in muscle recovery and digestive health. Many customers appreciate that the capsules are odorless and tasteless, making them easy to take without unpleasant aftertaste. Several users report noticeable benefits such as reduced muscle soreness and faster recovery times after workouts, highlighting its effectiveness as a post-exercise supplement. Others have shared that it helped improve digestive issues like constipation, contributing to better overall gut health.
The product’s quality is frequently praised, with users noting the absence of fillers, additives, and common allergens such as gluten, soy, and dairy. This clean formulation is important for those with sensitivities or dietary restrictions. The powder form also receives favorable remarks for its purity and ease of mixing into drinks, offering flexible dosing options.
Thorne L-Glutamine is NSF Certified for Sport®, which reassures athletes that the supplement is free from banned substances and manufactured under strict quality standards. This certification, along with Thorne’s reputation for rigorous testing, adds to consumer confidence.
While most feedback is positive, some users emphasize the importance of consistent use over time to experience benefits, and as with any supplement, individual results may vary. Overall, Thorne L-Glutamine is well-regarded for supporting gut integrity, immune function, and muscle repair, making it a trusted choice for both athletes and individuals seeking digestive support.
FAQs On Thorne L-Glutamine Capsules And Powder
You will find below all possible questions you may have on Thorne L-Glutamine with answers:
What Is The Recommended Dosage For Thorne L-Glutamine Capsules?
The typical dosage is 1 to 2 capsules taken two to three times daily, or as directed by your healthcare provider. Taking them with meals can improve absorption. This routine helps maintain optimal glutamine levels to support gut health, immune function, and muscle recovery effectively.
How Many Capsules Come In One Bottle Of Thorne L-Glutamine?
Each bottle of Thorne L-Glutamine contains 90 capsules, providing a convenient three-month supply if taken as recommended.
Can Thorne L-Glutamine Capsules Be Taken On An Empty Stomach?
While you can take them on an empty stomach, it’s generally advised to take the capsules with food to enhance absorption and reduce any potential digestive discomfort.
Are Thorne L-Glutamine Capsules Suitable For Daily Use?
Yes, these capsules are designed for daily use to support ongoing gut integrity, immune health, and muscle repair, especially during periods of physical stress or recovery.
Do The Capsules Contain Any Artificial Fillers Or Additives?
No, Thorne L-Glutamine capsules are free from artificial fillers, additives, gluten, soy, and dairy, making them a clean and hypoallergenic supplement choice.
Is There A Difference In Absorption Between The Capsules And Powder?
Both forms offer high bioavailability, but the powder allows for flexible dosing and quicker absorption, while capsules provide convenience and pre-measured doses.
How Long Does It Take To See Results From The Capsule Form?
Results can vary, but many users notice benefits such as improved digestion or reduced muscle soreness within a few weeks of consistent use.
Are The Capsules Vegan Or Vegetarian-Friendly?
Yes, the capsules use a plant-based hypromellose shell and contain no animal-derived ingredients, making them suitable for vegetarians and vegans.
Can Thorne L-Glutamine Capsules Support Gut Health?
Absolutely. L-glutamine is a key fuel source for intestinal cells, helping maintain the gut lining’s integrity and promoting digestive comfort.
Are There Any Side Effects Associated With The Capsule Form?
Side effects are rare but may include mild digestive issues like bloating or nausea. Most people tolerate the capsules well when taken as directed.
How Should The Capsules Be Stored?
Store the capsules in a cool, dry place away from direct sunlight and moisture to maintain their potency and shelf life.
Can Athletes Use Thorne L-Glutamine Capsules Safely?
Yes, these capsules are NSF Certified for Sport®, ensuring they are free from banned substances and safe for athletes to use.
Do The Capsules Help With Post-Workout Muscle Recovery?
Yes, L-glutamine supports muscle repair and reduces soreness, making these capsules beneficial for recovery after intense exercise.
Is It Safe To Combine Thorne L-Glutamine Capsules With Other Supplements?
Generally, yes. However, it’s best to consult your healthcare provider before combining supplements to avoid any interactions.
Are There Any Allergens In Thorne L-Glutamine Capsules?
No common allergens like gluten, soy, or dairy are present, making them suitable for most people with sensitivities.
How Many Times Per Day Should The Capsules Be Taken?
Typically, 1 to 2 capsules should be taken two to three times daily, depending on individual needs and healthcare advice.
Can These Capsules Be Used During Intermittent Fasting?
Yes, taking the capsules during fasting periods is possible, but consult your healthcare provider to ensure it fits your fasting goals.
Are Thorne L-Glutamine Capsules Third-Party Tested?
Yes, Thorne products undergo rigorous third-party testing to ensure purity, potency, and safety.
Is There Any Taste Associated With The Capsule Version?
No, the capsules are tasteless and odorless, making them easy to swallow without any unpleasant flavor.
Can Children Take Thorne L-Glutamine Capsules Under Supervision?
Children may take glutamine under medical supervision, but it’s important to consult a pediatrician before use.
Do The Capsules Support Immune Health?
Yes, L-glutamine plays a vital role in supporting immune cell function, helping maintain a healthy immune response.
How Quickly Are Thorne L-Glutamine Capsules Digested?
The capsules typically dissolve quickly in the stomach, allowing L-glutamine to be absorbed efficiently within a short time after ingestion.
Can The Capsules Be Opened And Mixed Into A Drink?
Yes, Thorne L-Glutamine capsules can be opened and their contents mixed into drinks or sprinkled on food. This is a handy option if you have trouble swallowing capsules or prefer to add glutamine to shakes or smoothies for easier consumption.
Are There Any Known Drug Interactions With The Capsule Form?
L-glutamine may interact with certain medications like hormonal contraceptives, cyclosporine, rifampin, and warfarin. These interactions can affect drug effectiveness or increase side effects, so it’s important to consult your healthcare provider before starting supplementation.
Is The Capsule Form Better For Travel Than The Powder?
Capsules are generally more travel-friendly because they’re compact, pre-measured, and less messy than powder. They’re easy to carry and don’t require mixing, making them convenient for on-the-go use.
How Much L-Glutamine Is In One Scoop Of Thorne L-Glutamine Powder?
One scoop of Thorne L-Glutamine powder contains about 5 grams of pure L-glutamine, providing a potent dose to support muscle recovery and gut health.
What Does Thorne L-Glutamine Powder Taste Like?
The powder has a neutral, almost tasteless profile, which makes it easy to mix into beverages without altering their flavor.
Can The Powder Be Mixed With Protein Shakes?
Yes, Thorne L-Glutamine powder mixes well with protein shakes, complementing protein intake and aiding muscle repair and recovery.
Is Thorne L-Glutamine Powder Safe For Long-Term Use?
Generally, it is safe for long-term use when taken as directed. However, consulting a healthcare professional before extended supplementation is recommended.
How Often Should You Take The Powder For Best Results?
Taking one scoop daily or divided doses throughout the day is common, but follow your healthcare provider’s advice for personalized dosing.
Is The Powder Form Better For Muscle Recovery Than Capsules?
The powder allows for larger, flexible doses, which some find more effective for muscle recovery, but both forms deliver glutamine efficiently.
Does Thorne L-Glutamine Powder Support Leaky Gut Repair?
Yes, glutamine is a key fuel for intestinal cells, helping to maintain and repair the gut lining, which supports leaky gut recovery.
Can The Powder Be Taken Before Bed?
Yes, taking glutamine powder before bed may support overnight muscle repair and gut healing.
What Liquid Works Best For Mixing The Powder?
Water, juice, or protein shakes work well to dissolve the powder quickly without affecting taste.
Is The Powder Suitable For People With Food Sensitivities?
Yes, it’s free from gluten, dairy, soy, and common allergens, making it suitable for sensitive individuals.
Can You Take Thorne L-Glutamine Powder With Other Amino Acid Supplements?
Generally, yes. Combining glutamine with other amino acids is common, but check with a healthcare provider to avoid interactions.
How Should Thorne L-Glutamine Powder Be Stored?
Store it tightly sealed in a cool, dry place away from sunlight to preserve freshness and potency.
Does The Powder Contain Any Added Sugars?
No, Thorne’s glutamine powder contains no added sugars or artificial ingredients.
Is The Powder More Cost-Effective Than The Capsules?
Typically, the powder offers more servings per container and can be more cost-effective for regular users.
How Long Does One Container Of Thorne L-Glutamine Powder Last?
A 513-gram container usually lasts about 90 servings, roughly three months with daily use.
Is There Any Grit Or Residue After Mixing The Powder?
No, the powder dissolves easily and does not leave gritty residue when mixed properly.
Can It Be Mixed With Hot Beverages Like Tea?
Yes, it can be added to warm drinks, but avoid very hot liquids to preserve glutamine’s stability.
What Time Of Day Is Ideal For Taking The Powder?
Morning, post-workout, or before bed are common times to maximize recovery and gut support.
Does The Powder Help With Workout Endurance?
Glutamine supports muscle recovery and immune health, which can indirectly improve endurance over time.
Can The Powder Be Used During Fasting?
Yes, it can be taken during fasting periods, but consult your healthcare provider to align with your fasting goals.
Is Thorne L-Glutamine Powder Suitable For Post-Surgery Recovery?
Yes, it supports tissue repair and immune function, making it beneficial during post-surgery healing.
Can Pregnant Or Breastfeeding Women Use The Powder Safely?
Pregnant or nursing women should consult their healthcare provider before using glutamine supplements.
Are There Any Risks In Taking More Than The Recommended Dose Of The Powder?
Exceeding recommended doses may cause digestive discomfort or other side effects; always follow dosing guidelines.
Is The Powder Tested For Heavy Metals Or Contaminants?
Yes, Thorne products undergo rigorous third-party testing to ensure purity and safety.
Can The Powder Be Taken On Rest Days From Exercise?
Yes, taking glutamine on rest days helps maintain muscle repair and gut health.
How Quickly Does The Body Absorb The Powdered Form?
The powder is absorbed rapidly, making glutamine available to cells shortly after ingestion.
Does The Powder Contain Any Flavoring Or Sweeteners?
No, it is free from flavorings and sweeteners, maintaining a pure, neutral taste.
Can The Powder Form Help Reduce Cravings Or Hunger?
Some users report glutamine helps stabilize blood sugar and reduce cravings, though effects vary individually.
Is Thorne L-Glutamine Powder Gluten-Free?
Yes, the powder is gluten-free and suitable for those with gluten sensitivities.
Can The Powder Be Used In Smoothies Without Altering The Taste?
Yes, it blends seamlessly into smoothies without changing flavor or texture.
Is It Okay To Split The Daily Dose Of The Powder Throughout The Day?
Yes, dividing the dose can improve absorption and maintain steady glutamine levels.
Can The Powder Be Used During A Gut Reset Protocol?
Absolutely, it’s often recommended to support gut lining repair during gut reset plans.
How Does Thorne’s Powder Compare To Other Glutamine Powders On The Market?
Thorne’s powder is known for purity, absence of fillers, and NSF Certified for Sport® status, making it a trusted choice.
Does The Powder Support Brain Function Or Mood?
Glutamine is a precursor to neurotransmitters, so it may support cognitive function and mood balance.
Can You Take Thorne L-Glutamine Powder Alongside Probiotics?
Yes, combining glutamine with probiotics can synergistically support gut health and immune function.
Final Thoughts
Thorne L-Glutamine capsules and powder both provide a high-quality source of L-glutamine, an amino acid essential for supporting gut health, immune function, and muscle recovery. The choice between the two forms depends largely on personal preference and convenience.
Thorne L-Glutamine Capsules offer a convenient, pre-measured dose of 500 mg per capsule, making them easy to take on the go without the need for mixing or measuring. They are free from common allergens such as gluten, soy, and dairy, and come in a hypoallergenic capsule shell. Capsules are ideal for those who prefer a simple, portable supplement and consistent dosing throughout the day.
Thorne L-Glutamine Powder provides a larger dose per serving (about 5 grams per scoop) and is free from fillers or additives. This form is well-suited for individuals who want to customize their dosage or prefer mixing their supplement into water, juice, or smoothies. The powder is also allergen-free and highly bioavailable, supporting rapid absorption and utilization by the body.
Both forms are NSF Certified for Sport®, ensuring they meet rigorous standards for purity and are free from banned substances, which is particularly important for athletes. Thorne’s commitment to quality includes multiple rounds of testing to guarantee potency and safety.
In terms of effectiveness, L-glutamine supplementation is especially beneficial during periods of physical stress, intense exercise, injury recovery, or digestive challenges, as it helps maintain intestinal cell integrity, supports immune cell function, and aids muscle repair. While glutamine is naturally produced by the body, supplementation can help replenish depleted levels to promote overall health and resilience.
In summary, Thorne L-Glutamine capsules and powder both deliver pure, high-quality glutamine to support gut, immune, and muscle health. Capsules offer convenience and ease of use, while the powder allows for flexible dosing and mixing options. Choosing between them depends on your lifestyle, dosing preferences, and how you prefer to incorporate supplements into your routine. Both forms align with Thorne’s reputation for clean, science-backed supplements trusted by health professionals and athletes alike.